Thank you very much for your insightful suggestion, which is very helpful in designing experiments.

Hi David, we could start with three-time points during pregnancy (early, mid and late gestation). And perhaps add a time point after delivery? Gut and splenic T cells would be good places to start. But perhaps the placenta as well? (Then it will be more than ten conditions.) Yes, TCRseq + Clonal expansion would be a great idea. Happy to chat more!!