To second this point, since the goal is to understand the "natural states" that T cells can adopt in various environmental conditions, profiling KO T cells are out of scope per se. But if a genetically engineered mouse serves as a disease model, particularly if the mutation is extrinsic to T cells, then it is within the scope of the ImmGen T project.
To second this point, since the goal is to understand the "natural states" that T cells can adopt in various environmental conditions, profiling KO T cells are out of scope per se. But if a genetically engineered mouse serves as a disease model, particularly if the mutation is extrinsic to T cells, then it is within the scope of the ImmGen T project.